Your new friendly neighbourhood Spider-Man has spun himself a $US65 million ($A63.40 million) opening weekend and $US140 million in his first six days at US theatres.

Overseas, Sony's The Amazing Spider-Man added $US129.1 million, raising its international total to $US201.6 million and worldwide haul to $US341.2 million since it began rolling out a week earlier in some foreign markets.

The movie started off as a smaller domestic moneymaker than the previous three Spidey films, but it laid to rest objections that it was too soon to relaunch the superhero franchise.

The new origin story for the Marvel Comics web-slinger comes just five years after Spider-Man 3, Tobey Maguire and director Sam Raimi's final movie in a series that shattered box-office records.

"This was never modelled or was never meant to be Spider-Man 4. This was always a relaunch with a new cast and different stories to tell, and quite frankly, it succeeded beyond our imaginations," said Rory Bruer, Sony's head of distribution.

The previous weekend's No.1 film, Universal's teddy-bear comedy Ted, fell to second place with $US32.6 million, raising its domestic total to $US120.2 million.

Among new releases, Oliver Stone's drug-war thriller Savages opened at No.4 with a solid $US16.2 million weekend, also for Universal. Paramount's concert film Katy Perry: Part of Me failed to pack in the pop star's fans, debuting at a distant No.8 with just $US7.2 million.

Going into wide release after two weekends in a handful of theatres, Woody Allen's ensemble romance To Rome with Love broke into the top 10 with $US3.5 million. The Sony Pictures Classics release lifted its domestic total to $US5.3 million.

The Amazing Spider-Man bumped up US receipts, with Hollywood pulling in an estimated $US200 million overall for the weekend, according to box-office tracker Hollywood.com. That's a 28.6 per cent increase over the same weekend last year, when Transformers: Dark of the Moon led with $US47.1 million in its second weekend.

Leading up to the domestic debut of Amazing Spider-Man last Tuesday, Hollywood had expectations of a six-day total of around $US120 million for the film by the end of the Fourth of July holiday weekend. That proved a conservative projection, but studio executives genuinely were uncertain how well the film might do so close on the heels of the previous Spider-Man series.

"To expect the kind of numbers the first Spider-Man did or the second or third would have been kind of reaching," said Hollywood.com analyst Paul Dergarabedian. "For a reboot that people definitely were on the fence about initially, I think this is a really strong performance."

Andrew Garfield stars as teen orphan Peter Parker, who becomes a vengeful vigilante and later an urban protector after the bite of a mutant spider gives him super strength, agility and senses. Marc Webb ((500) Days of Summer) directed the film, which co-stars Emma Stone, Rhys Ifans, Sally Field and Martin Sheen.

Amazing Spider-Man had a price advantage over its predecessors. This was the first 3D Spidey movie, earning 44 per cent of its domestic revenues from 3D screenings, which cost a few dollars more than 2D shows.

The film is the centrepiece of a huge superhero (northern) summer that started with The Avengers and continues with the July 20 debut of The Dark Knight Rises, the finale of Christopher Nolan and Christian Bale's Batman trilogy.

Director Stone's Savages chronicles a bloody war between California marijuana growers and a merciless Mexican cartel trying to muscle into their business. The ensemble cast includes Salma Hayek, John Travolta, Benicio Del Toro, Blake Lively, Taylor Kitsch and Aaron Johnson.

Perry's Part of Me raised its domestic total to $US10.3 million since opening on Thursday. Her mix of 3D stage show and backstage documentary was a bust compared to such concert hits as 2008's Hannah Montana Miley Cyrus: Best of Both Worlds Concert, which opened with $US31.1 million, and last year's Justin Bieber: Never Say Never, which premiered with $US29.5 million.

Estimated ticket sales are for Friday through to Sunday at US and Canadian theatres, according to Hollywood.com.

1. The Amazing Spider-Man, $US65 million.

2. Ted, $US32.6 million.

3. Brave, $US20.2 million.

4. Savages, $US16.2 million.

5. Magic Mike, $US15.6 million.

6. Tyler Perry's Madea's Witness Protection, $US10.2 million.

7. Madagascar 3: Europe's Most Wanted, $US7.7 million.

8. Katy Perry: Part of Me, $US7.2 million.

9. Moonrise Kingdom, $US4.6 million.

10. To Rome with Love, $US3.5 million.